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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
KLHL36
All Species:
27.27
Human Site:
Y435
Identified Species:
60
UniProt:
Q8N4N3
Number Species:
10
Phosphosite Substitution
Charge Score:
0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N4N3
NP_079007.2
616
69896
Y435
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Chimpanzee
Pan troglodytes
XP_001151795
616
69864
Y435
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Rhesus Macaque
Macaca mulatta
XP_001112834
616
69878
Y435
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Dog
Lupus familis
XP_546799
616
70093
Y435
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8R124
613
69932
Y433
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Rat
Rattus norvegicus
Q66HD2
613
69917
Y433
A
G
L
P
R
F
T
Y
G
H
A
G
T
I
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509771
765
85643
Y584
A
G
L
P
R
F
T
Y
G
H
A
G
T
V
Y
Chicken
Gallus gallus
Q5ZLD3
629
70952
E450
S
Y
V
A
K
M
N
E
P
H
Y
G
H
A
G
Frog
Xenopus laevis
NP_001086711
635
71326
E456
N
Y
V
A
K
M
N
E
P
H
Y
G
H
A
G
Zebra Danio
Brachydanio rerio
Q503R4
605
68451
G435
E
L
P
K
F
T
Y
G
H
A
G
T
I
H
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VUU5
623
68905
L455
A
P
M
T
T
R
R
L
G
V
A
V
A
V
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
99.6
96.5
N.A.
85.7
86.1
N.A.
70.1
37.3
36.6
61.8
N.A.
29.7
N.A.
N.A.
N.A.
Protein Similarity:
100
100
100
98.3
N.A.
92.2
92.2
N.A.
74.7
58.5
57.9
75.6
N.A.
47.3
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
93.3
13.3
13.3
0
N.A.
20
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
33.3
26.6
0
N.A.
33.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
73
0
0
19
0
0
0
0
0
10
73
0
10
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
0
19
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
10
64
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
64
0
0
0
0
0
10
73
0
10
82
0
0
19
% G
% His:
0
0
0
0
0
0
0
0
10
82
0
0
19
10
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
10
55
0
% I
% Lys:
0
0
0
10
19
0
0
0
0
0
0
0
0
0
10
% K
% Leu:
0
10
64
0
0
0
0
10
0
0
0
0
0
0
10
% L
% Met:
0
0
10
0
0
19
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
0
0
0
0
19
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
10
64
0
0
0
0
19
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
64
10
10
0
0
0
0
0
0
0
0
% R
% Ser:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
10
10
10
64
0
0
0
0
10
64
0
0
% T
% Val:
0
0
19
0
0
0
0
0
0
10
0
10
0
19
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
19
0
0
0
0
10
64
0
0
19
0
0
0
64
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _